Synthesis of Some Analogs of Bradykinin Hormone Using Modified Solid Phase Peptide Synthesis and Microwave Technique (Part 1) - Egyptian Knowledge Bank

1219

Synthesis of Some Analogs of Bradykinin Hormone Using Modified Solid Phase Peptide Synthesis and Microwave Technique (Part 1)

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Last updated: 01 Jan 2025

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Abstract

THREE analogs of Bradykinin, (Lys1) BK, (Lys9) BK and (Lys1, 9) …… BK were synthesized by modified solid phase peptide synthesis with the application of microwave energy. The effect of the replacement of Arg1,9 by Lys on the salt bridge between the guanidine group of Arg1 and the carboxyl group of Arg9, was investigated. The analogues will be tested in vitro for their effect on heart rate of rats and in isolated organ for the arterial pressure.

DOI

10.21608/ejchem.2010.1219

Keywords

Bradykinin, Modified solid phase peptide synthesis and Microwave energy

Volume

Article Issue

Related Issue

289

Issue Date

2010-04-01

Receive Date

2010-03-17

Publish Date

2010-04-30

Page Start

267

Page End

277

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 53_Issue 2_Pages 267-277.pdf

PDF . 522.4kB

Link

https://ejchem.journals.ekb.eg/article_1219.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1219

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Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

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