Solid Phase Synthesis of I25 Labeled Insulin Fragments. Part III. Synthesis of 125-I-Insulin Fragment B15-18 Leu-Tyr(I2)-Leu-Val - Egyptian Knowledge Bank

1178

Solid Phase Synthesis of I25 Labeled Insulin Fragments. Part III. Synthesis of 125-I-Insulin Fragment B15-18 Leu-Tyr(I2)-Leu-Val

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Last updated: 01 Jan 2025

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Abstract

NOWA DAYS, synthesis of biological active peptides has been found in an impressive success. This has been achieved by development of new techniques, using new reagents and easy reach. A new approach to radio-peptides synthesis has been investigated in an effort to overcome the technical difficulties of separation, purification and identification of the prepared peptide fragments. In a series of solid-phase peptide synthesis of labeled insulin fragments, we have prepared 125-I-Insulin fragment Bl 5-18. In this research work we discussed the synthesis of Insulin fragment B15-18 Labeled with Leu-Tyr(I 2 )-Leu-Val.

DOI

10.21608/ejchem.2012.1178

Keywords

Amino acids, Insulin, iodine 125, Labeling, Peptide hormones and Synthesis

Volume

Article Issue

Related Issue

284

Issue Date

2012-12-01

Receive Date

2013-04-08

Publish Date

2012-12-30

Page Start

639

Page End

647

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 55_Issue 6_Pages 639-647.pdf

PDF . 454.3kB

Link

https://ejchem.journals.ekb.eg/article_1178.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1178

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Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

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