New Approaches for the Synthesis of Thiophene Derivatives with Antitumor Activities - Egyptian Knowledge Bank

1173

New Approaches for the Synthesis of Thiophene Derivatives with Antitumor Activities

Article

Last updated: 22 Jan 2023

Subjects

Abstract

TETRAHYDROBENZO[B]THIOPHENE derivatives 3a,b and 5a,b were synthesized followed by the alkylation of some derivatives. The antitumor evaluation of the newly synthesized products against three cancer cell lines, namely breast adenocarcinoma (MCF-7), non-small cell lung cancer (NCI-H460) and CNS cancer (SF-268) was recorded. Some of the synthesized compounds show high inhibitory effects.

DOI

10.21608/ejchem.2012.1173

Keywords

THIOPHENE, Pyridine, Pyrazole and Antitumor

Volume

Article Issue

Related Issue

283

Issue Date

2012-10-01

Receive Date

2012-12-13

Publish Date

2012-10-30

Page Start

549

Page End

560

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 55_Issue 5_Pages 549-560.pdf

PDF . 402.7kB

Link

https://ejchem.journals.ekb.eg/article_1173.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1173

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Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Details

Type