Synthesis of Some Heterocyclic Molecuoles from New Benzoxazinones and Quinazolinones - Egyptian Knowledge Bank

1135

Synthesis of Some Heterocyclic Molecuoles from New Benzoxazinones and Quinazolinones

Article

Last updated: 22 Jan 2023

Subjects

Abstract

THE BENZOXAXAZINONE 3 was prepared and treated with …... hydrazine hydrate, hydroxylamine hydrochloride, and o-phenylenediamine to give different quinazolinones 4,5 and benzoimidazoles 6, 7, respectively.Product 4 reacted with different aldehydes forming different Schiff's basses 9,10a - e. Also, it reacted with different Grignard reagents giving alcohols(11a,b) and ketones 11c,d, according to the bulkiness of the reagent. Finally, dibromo, monobromoamino and diaminoquinazolinones (12,13 a-d) & (14 a-d) were prepared upon addition of bromine to 4, followed by reacting different amines according to their molar ratios. Some benzoxazinone, and quinazolinone derivatives were tested for their antifungal and antibacterial activities and gave promising results.

DOI

10.21608/ejchem.2012.1135

Keywords

Quinazolinones, Benzoxazinones and Schiff’s base

Volume

Article Issue

Related Issue

279

Issue Date

2012-02-01

Receive Date

2012-03-07

Publish Date

2012-02-28

Page Start

Page End

110

Print ISSN

0449-2285

Online ISSN

2357-0245

Article File

EJCHEM_Volume 55_Issue 1_Pages 99-110.pdf

PDF . 426.0kB

Link

https://ejchem.journals.ekb.eg/article_1135.html

Detail API

https://ejchem.journals.ekb.eg/service?article_code=1135

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Type Code

292

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

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Details

Type