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161136

The Frequency of Tumor Necrosis Factor-alpha Gene Polymorphism in Patients with Chronic Immune Thrombocytopenia.

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pediatrics

Abstract

Background: The aim of this study was to reveal the frequency of Necrosis Factor _Alpha Gene Polymorphism in evaluation of severity and outcome of chronic immune thrombocytopenia in pediatric department of Zagazig University hospitals.
Methods: We conduct a retrospective case control on 40 children diagnosed with chronic ITP and 40 age and sex healthy matched subjects as a control recruited from outpatient hematology clinic Faculty of Medicine, Zagazig University.
Results: We found a highly significant difference between ITP group and control group as regarding TNF-α alleles where A allele was expressed in 43.7% of cases versus 17.5% 0f control, P value

DOI

10.21608/zumj.2021.16776.1504

Keywords

TNF-alpha, Immune thrombocytopenia, PCR-ARMS

Authors

First Name

nehal

Last Name

elgohary

MiddleName

tarek

Affiliation

pediatric department faculty of medicine zagazig university

Email

crazynonna89@gmail.com

City

zagazig

Orcid

0000-0002-7550-3927

First Name

usama

Last Name

elsafy

MiddleName

roshdy

Affiliation

pediatric department,faculty of medicine,zagazig university

Email

usamaelsafy@gmail.com

City

zagazig

Orcid

-

First Name

marwa

Last Name

mohamed

MiddleName

zakaria

Affiliation

pediatric department,faculty of medicine,zagazig university

Email

marwazakaria@gmail.com

City

zagazig

Orcid

-

First Name

Nermin

Last Name

Abdel-Fattah

MiddleName

Raafat

Affiliation

Medical Biochemistry, Faculty of Medicine, Zagazig University, Egypt

Email

nerminraafat@gmail.com

City

Zagazig

Orcid

-

Volume

29

Article Issue

1

Related Issue

38591

Issue Date

2023-01-01

Receive Date

2019-09-12

Publish Date

2023-01-01

Page Start

155

Page End

160

Print ISSN

1110-1431

Online ISSN

2357-0717

Article File

ZUMJ_Volume 29_Issue 1_Pages 155-160.pdf

PDF . 371.1kB

Link

https://zumj.journals.ekb.eg/article_161136.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=161136

Order

19

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

The Frequency of Tumor Necrosis Factor-alpha Gene Polymorphism in Patients with Chronic Immune Thrombocytopenia.

Details

Type

Article

Created At

22 Jan 2023