Background: Reducing nitrogen-absorbing mucosa in the mastoid cavity , preventing cholesteatoma recurrence in patients with dysfunctional eustachian tube and avoiding mastoid cavity problems are The main goals of mastoid cavity obliteration . Platelet rich plasma represents a recent biotechnology providing a high concentration of growth factors, which found to be highly effective in healing acceleration and infection prevention.
objectives: To evaluate using of silicone blocks and platelet rich plasma in canal wall reconstruction and mastoid cavity obliteration after mastoidectomy .
Patients and Methods: Our study applied on 20 patients with cholesteatoma who underwent mastoid obliteration with silicone blocks and platelet rich plasma ,The used surgical technique composed four major steps: First, Mastoidectomy and the middle ear clearing from all pathologic lesions were achieved Then, reconstruction of the canal wall then filling up the the epitympanic space and the mastoidectomized cavity by silicone blocks. Finally, covering the surface of the silicone blocks by Platelet rich plasma and Temporalis fascia ± bone pate and Reinforcing the reconstructed canal wall by anterior based periosteal flap .
Results: (90%) of the operated cases maintained a near normal shape and contour with healed ear drum, The air-bone gap mean was improved by about 19 dB (P< .001)
Conclusion: Silicone blocks and platelet rich plasma considered as a good materials for mastoid cavity obliteration.
Key Words. Cholesteatoma, Silicones, platelet rich plasma ,Mastoid.