Beta
ManageSearchChatDiscover
265742

Circulating and Mucosal Associated Type 2 Innate Lymphoid Cells in Asthma

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Chest

Abstract

Abstract
Background: Type 2 innate lymphoid cells (ILC2s) are introduced as a key player in type 2 inflammation. Objectives: To assess the correlation between ILC2s in peripheral blood, sputum, and colonic biopsies among patients with asthma, and to assess the relation between ILC2s frequency and severity of asthma. Methods: ILC2s numbers were assessed in peripheral blood, and sputum among 29 patients with asthma (asthma group) and 29 healthy controls (control group). Colonic biopsies were obtained from twelve mild to moderate asthma patients and nine healthy controls. ILC2s were determined by multicolor flow cytometer in all specimens. Results: ILC2s numbers in peripheral blood were higher among the asthma group compared to the control group (P

DOI

10.21608/zumj.2022.159017.2631

Keywords

Keywords: Innate lymphoid cells, Asthma, Peripheral blood, Colon, Sputum

Authors

First Name

Lobna

Last Name

Alqurashi

MiddleName

A.

Affiliation

Medical micro biology and immunology Department, Faculty of medicine, Zagazig University, Zagazig, Egypt

Email

alqurashilobna@yahoo.com

City

Zagazig

Orcid

-

First Name

hoda

Last Name

mohamed

MiddleName

fathi

Affiliation

faculty of medicine zagazig university clinical pathology department

Email

dodoebian2015@yahoo.com

City

Zagazig

Orcid

-

First Name

Ahmed

Last Name

El-Gebaly

MiddleName

M.

Affiliation

Tropical Medicine, Faculty of Medicine, Zagazig University, Zagazig, Sharkia, Egypt

Email

icegebo2011@yahoo.com

City

Zagazig

Orcid

0000-0002-5767-1855

First Name

Nadia

Last Name

El-Akabawy

MiddleName

M.

Affiliation

Department of Medical Histology and Cell Biology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Email

dr_nadia2007@yahoo.com

City

Zagazig

Orcid

-

First Name

Saad

Last Name

Samra

MiddleName

R.

Affiliation

Chest department, Faculty of medicine, Zagazig University, Zagazig, Egypt

Email

saad_samra2003@yahoo.com

City

Zagazig

Orcid

-

First Name

Lamiaa

Last Name

Zake

MiddleName

Gaber

Affiliation

Department of Chest diseases, Faculty of Medicine, Zagazig University, Egypt

Email

lamiagaber199@gmail.com

City

-

Orcid

0000-0002-4922-860x

Volume

28

Article Issue

6.1

Related Issue

37722

Issue Date

2022-11-01

Receive Date

2022-08-31

Publish Date

2022-11-01

Page Start

265

Page End

275

Print ISSN

1110-1431

Online ISSN

2357-0717

Article File

ZUMJ_Volume 28_Issue 6.1_Pages 265-275.pdf

PDF . 369.1kB

Link

https://zumj.journals.ekb.eg/article_265742.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=265742

Order

1,047

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Circulating and Mucosal Associated Type 2 Innate Lymphoid Cells in Asthma

Details

Type

Article

Created At

22 Jan 2023