Abstract:
Background and Purpose: Seizures are a serious complication of spontaneous intracerebral hemorrhage (sICH) which increases morbidity of the patients.
Patients and Methods; cross sectional analysis of patients admitted to Zagazig Neurology Department and Intensive Care Unit(ICU) (n=125and follow-up to 6 months) for detection of early and late onset seizures. within 7 days of ICH and among 7-day survivors for detection of early seizures (ES) and late seizures (LSs) occurring >7 days from ICH. Using CT brain and CT angiography for diagnosis and to measure the volume of hemorrhage, also using CAVE score for evaluation or ES and LSS.
Results: Of our study on 125 patients with sICH 58 were males and 67 were females , there were cortical hge 36% , BG(Basal Ganglia) 23.2%, Thalamic he 25.6%,cerebellar he 10.4% and brain stem was 4.8%, while intraventricular extenstion was 9.6% and with SAH 7.2 %, also 18 patients (14.4%) had ES within 7 days of sICH. Among the 7-day survivors, 10 patients (8%) developed LSs.
There were a stasistically significant association between early ES and LSs with the volume of intracerebral hemorrhage and CAVE scale.
Conclusions: about 14 % of patients with sICH will develop seizures with in the first 7 days . while 8% will develop LSs after one week of sICH The risk of this adverse outcome can be estimated by CAVE scale which is a simple score based on baseline variables.