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Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Obstetrics & Gynaecology

Abstract

Conservative ovarian management plans for young patients having cervical cancer is now widely accepted, Preservation of one or both ovaries in patients with cervical adenocarcinoma is still a controversial issue but preservation of the ovaries in patients with certain criteria might be considered more important to those patients having cancer cervix who were diagnosed in the early stage.So it is important to establish the selection criteria of cervical cancer patients who will be eligible for preservation of ovarian function.The aim of our study was to identify suitable cervical cancer patients who will benefit from preservation of their ovaries and to detect the survival benefits and patients outcome.Patients and methods: Performing the current prospective cohort study was done in the period from September2014to October2019.We included60females with cancer cervix stage(I-II),we divided patients into two groups the first group included30females underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy and the second group included30patients and underwent total abdominal hysterectomy with preservation of the ovaries.We followed the patients for5years.Results:we showed that patients with preserved ovaries were younger, with lower T stage,earlier(FIGO)stage(IA-B),ower histological grades.Five-year cancer specific survival-rate was higher in the ovarian conservation group than in the oophorectomy group, OS-rate was higher in the ovarian conservation group than in the oophorectomy group.Conclusion:Our study showed that preservation of ovaries in in young females patients who diagnosed with early stage cervical carcinoma(FIGO I-II)is associated with a favorable outcome due to avoiding induction of premature surgical menopase without increasing risks of ovarian metastases or increasing cervical cancer related death-risks.

DOI

10.21608/zumj.2020.38315.1915

Keywords

Cervical Cancer, ovarian preservation, Staging

Authors

First Name

Mohammad

Last Name

Badr

MiddleName

Samir

Affiliation

Department of Gynecology and Obstetrics, Zagazig University Faculty of Medicine, Zagazig, Egypt

Email

2362044@gmail.com

City

Zagazig

Orcid

-

First Name

Amr

Last Name

Elnemr

MiddleName

Abmohsen

Affiliation

gynecology and Obstetrics Department, Faculty of medicine, Zagazig University.

Email

amrabmohsen@yahoo.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Alattar

MiddleName

Z

Affiliation

Department of Clinical Oncology and Nuclear Medicine, Zagazig University Faculty of Medicine, Zagazig, Egypt

Email

ahmed.alattar@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Alabiad

MiddleName

Ali

Affiliation

Pathology Department, Faculty of Medicine, Zagazig University

Email

maabyad@medicine.zu.edu.eg

City

-

Orcid

0000-0001-5692-7639

First Name

Gamal

Last Name

Osman

MiddleName

-

Affiliation

Department of General surgery, Faculty of Medicine, Zagazig University Zagazig, Egypt

Email

gamal.osman@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

El-Taher

MiddleName

K

Affiliation

Department of General surgery, Faculty of Medicine, Zagazig University Zagazig, Egypt

Email

ahmed_kamal@gmail.com

City

-

Orcid

-

Volume

28

Article Issue

5

Related Issue

36360

Issue Date

2022-09-01

Receive Date

2020-08-07

Publish Date

2022-09-01

Page Start

1,009

Page End

1,015

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_112666.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=112666

Order

13

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Oncological Outcomes and Safety of Ovarian Preservation in Early Stage Carcinoma of the Cervix

Details

Type

Article

Created At

22 Jan 2023