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227992

Neuropathological changes and neurological manifestations in COVID-19 cases: A narrative review

Article

Last updated: 22 Jan 2023

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Subjects

-

Tags

Internal Medicine

Abstract

Background: Corona virus disease 2019 (COVID-19) has a lot of effects on the different tissues of human body particularly the respiratory system. Recently, there have been a lot of evidences that severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) has some effects on the nervous system especially brain tissues. In the early months of COVID-19 pandemic, the physicians focused on treating and dealing with lung damage and circulatory system support, but later the effects of neurological deterioration started to appear. In this review article we will discuss the different routes of administration of the virus into the central nervous system, neuropathological changes in the brain tissue, clinical neurological manifestations of the patients with COVID-19 and the histopathological changes in COVID-19 cases with neurological findings.
Conclusions: the brain tissue is affected by SARS-CoV-2 infection which causes a lot of neuropathological changes and manifests by different neurological signs and symptoms which are to be discussed.

DOI

10.21608/zumj.2022.125967.2494

Keywords

COVID-19, neuropathology, SARS-CoV-2, Guillain Barre Syndrome, Neurological manifestations

Authors

First Name

Ahmed

Last Name

Abdelgaleel

MiddleName

Ayman

Affiliation

Undergraduate medical student, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

ahmedbahrawi34@gmail.com

City

Zagazig

Orcid

-

First Name

Ahmed

Last Name

Hemely

MiddleName

Khaled

Affiliation

Undergraduate medical student, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

ak688924@gmail.com

City

Zagazig

Orcid

-

First Name

Momen

Last Name

Elkomy

MiddleName

Khaled

Affiliation

Undergraduate medical student, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

20512018100572@medicine.zu.edu.eg

City

Zagazig

Orcid

-

First Name

Mahmoud

Last Name

Sateeh

MiddleName

Mohamed

Affiliation

Undergraduate medical student, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

mahmoud.sateh1212@gmail.com

City

Zagazig

Orcid

-

First Name

Hossam

Last Name

Hassan

MiddleName

Abdelshafy

Affiliation

Undergraduate medical student, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

hossam.abdelshafy110200@gmail.com

City

Zagazig

Orcid

-

First Name

Sara

Last Name

Jbeil

MiddleName

Mahmoud

Affiliation

Undergraduate medical student, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

saramahmoudjpeil@gmail.com

City

Zagazig

Orcid

-

First Name

Ahmed

Last Name

Fawzy

MiddleName

Fawzy

Affiliation

Undergraduate medical student, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

ahmedfawzy1872@gmail.com

City

Zagazig

Orcid

-

First Name

Rehab

Last Name

El-Sokkary

MiddleName

Hosny

Affiliation

Medical microbiology and immunology, faculty of medicine, Zagazig University, Zagazig, Egypt

Email

rehab_elsokkary@yahoo.com

City

Zagazig

Orcid

0000-0002-8135-7671

Volume

28

Article Issue

5

Related Issue

36360

Issue Date

2022-09-01

Receive Date

2022-03-07

Publish Date

2022-09-01

Page Start

912

Page End

917

Print ISSN

1110-1431

Online ISSN

2357-0717

Article File

ZUMJ_Volume 28_Issue 5_Pages 912-917.pdf

PDF . 319.2kB

Link

https://zumj.journals.ekb.eg/article_227992.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=227992

Order

1

Type

Review Articles

Type Code

349

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023