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206986

Global Longitudinal Strain to Predict Pacing Induced Ventricular Dysfunction

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Cardiology

Abstract

Background: Chronic RV pacing leads to asynchronous left ventricular activation which in turn predisposes to deleterious effects on the left ventricular (LV) function leading to reduction in the left ventricular ejection fraction (LVEF) and pacing induced ventricular dysfunction (PIVD).
Aim: The aim was to study the effects of right ventricular pacing on left ventricular function by deformation imaging using 2D speckle tracking echocardiography.
Methods: The study included 50 patients with normal LVEF (≥55%) who underwent single and dual chamber pacemaker implantation for various conduction disturbances. LVEF and global longitudinal strain measurements assessed by 2D special tracking echocardiography at baseline and at 1 month and 12 months follow up.
Results At 12 months follow up, 14 (28%) patients developed PIVD; 4 of which developed pacemaker induced cardiomyopathy (PICM). At the one month follow up, the GLS was significantly reduced in the 14 patients who subsequently developed PIVD at 12 months, compared to those who did not show significant decline in EF. (n = 38) (GLS -12.46 ± 2.77 vs-16.05-± 2.57 vs. -16.4 respectively; p = 0.001). The ejection fraction was also significantly reduced in this group at 1 month follow up compared to those without PIVD (EF 53.57 ± 5.05 vs 61.28 ± 4.67 respectively; p value= 0.001) When the 4 patients with PICMP were excluded, only the 1-month GLS was significantly reduced compared to baseline.
Conclusion: Global longitudinal strain measurements after pacemaker provides valuable data in predicting patients who subsequently develop pacemaker induced dysfunction.

DOI

10.21608/zumj.2021.86817.2289

Keywords

Right Ventricle, Pacing, global strain

Authors

First Name

Noran

Last Name

Khalil

MiddleName

-

Affiliation

Cardiology Department, Faculty of Medicine, Tanta University

Email

noran_cardio@yahoo.com

City

Tanta

Orcid

-

First Name

Medhat

Last Name

Ashmawy

MiddleName

Mohamed

Affiliation

Cardiology Department, Faculty of Medicine, Tanta University

Email

medhatashmawy56@outlook.com

City

Tanta

Orcid

-

First Name

Ayman

Last Name

El Saied

MiddleName

Mohamed

Affiliation

Cardiology Department, Faculty of Medicine, Tanta University

Email

alsaieda1@yahoo.com

City

Tanta

Orcid

-

First Name

Samia

Last Name

Sharaf El Din

MiddleName

Mahmoud

Affiliation

Cardiology Department, Faculty of Medicine, Tanta University

Email

samiasharaf9@gmail.com

City

Tanta

Orcid

-

First Name

Yasser

Last Name

El Barbary

MiddleName

-

Affiliation

Cardiology Department, Faculty of Medicine, Tanta University

Email

yelbarbary@yahoo.com

City

Tanta

Orcid

-

Volume

28

Article Issue

4

Related Issue

35321

Issue Date

2022-07-01

Receive Date

2021-07-21

Publish Date

2022-07-01

Page Start

832

Page End

838

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_206986.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=206986

Order

27

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

Global Longitudinal Strain to Predict Pacing Induced Ventricular Dysfunction

Details

Type

Article

Created At

22 Jan 2023