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103249

EFFECT OF NITRIC OXIDE IN CHRONIC EXPERIMENTAL TOXOPLASMA GONDII INFECTION: HISTOPATHOLOGICAL AND HISTOCHEMICAL STUDY

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Pathology

Abstract

Aim of the work: To evaluate the histopathological alterations and immuno-histochemical pattern in chronic Toxoplasma gondii infection, and to evaluate the role aminoguanidine in experimental toxoplasmosis.

Subjects and methods: This study was carried out on 48 laboratory-bred male Swiss albino mice which were divided into 4 groups (non-infected control; infected control; infected and treated with spiramycin; infected and treated with aminoguanidine). The effect of the used drugs was assessed using parasitological, histopathological and immunohistochemical approaches.

Results: There was highly significant (P

DOI

10.21608/zumj.2020.29297.1839

Keywords

Toxoplasmosis, Aminoguanidine, Immunohistochemical, Spiramycin, iNOS

Authors

First Name

Marwa

Last Name

Omar

MiddleName

-

Affiliation

Medical parasitology ,faculty of medicine , Zagazig university ,Zagazig ,Egypt

Email

rycmarwa@gmail.com

City

Zagazig

Orcid

-

First Name

Beessa Abaza

Last Name

Abaza

MiddleName

El-Sayed

Affiliation

Medical parasitology ,faculty of medicine ,Zagazig university ,Zagazig ,Egypt

Email

beessa_abaza@hotmail.com

City

Zagazig

Orcid

-

First Name

Esraa

Last Name

Mousa

MiddleName

-

Affiliation

Medical parasitology ,faculty of medicine ,Zagazig university ,Zagazig ,Egypt

Email

esraasaleh2311@gmail.com

City

-

Orcid

-

First Name

Hayam

Last Name

Rashed

MiddleName

Elsaid

Affiliation

department of pathology, zagazig university egypt

Email

hayam_rashed@yahoo.com

City

sharqia

Orcid

-

First Name

Tahani

Last Name

Farag

MiddleName

Ismail

Affiliation

Medical parasitology ,faculty of medicine ,Zagazig university ,Zagazig ,Egypt

Email

tahaniabdelkhalik2015@gmail.com

City

Zagazig

Orcid

0000-0002-9240-9887

Volume

27

Article Issue

5

Related Issue

27391

Issue Date

2021-09-01

Receive Date

2020-05-12

Publish Date

2021-09-01

Page Start

938

Page End

947

Print ISSN

1110-1431

Online ISSN

2357-0717

Article File

ZUMJ_Volume 27_Issue 5_Pages 938-947.pdf

PDF . 1.3MB

Link

https://zumj.journals.ekb.eg/article_103249.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=103249

Order

511

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023