Background: Warts are a common sight in dermatology and they constitute the commonest cutaneous manifestation of human papilloma virus (HPV) infection. A variety of modalities has been used and treatment may be invasive and/or conservative. Therefore, the aim of this study was to evaluate the efficacy and safety of intralesional Candida antigen injection in the treatment of common warts.
Material and Methods: At outpatient dermatology clinic, 28 patients with common warts of the hands and feet were treated with intralesional Candida antigen. Side effects as well as improvements in texture after each session and after the final treatment were documented. The patients treated by 0.1 intralesional candidal injection once weekly maximum for 5 sessions for 5 weeks or less if complete recovery occur.
Results: Patient's response to treatment was assessed clinically and we found the efficacy of Candida antigen in the treatment of common wart by 35.7%. In our study, all reported side effects were mild, tolerable, and transient and did not necessitate stoppage of treatment in any of the studied patients. No recurrence during 6 months follow up .
Conclusion: Intralesional Candida injection is an effective and safe modality for the treatment of common warts.
Keywords: Warts, Candida injections, Immunotherapy.