Objective: The aim of the current study was to study the correlation of QRS dispersion with the severity of coronary artery lesion in patients with NSTEMI detected by GENSINI score (short term outcome). Methods: The whole study group included 96 (63 males and 33 females) patients presented with NSTEMI. Age ranged from 46 and 75 years with a mean of 57.4 ± 6.8. Table (7) summarizes clinical baseline and laboratory data of the studied patients. Results: study was include 96 consecutive patients whom were admitted to Cardiology Care Unit for NSTEMI in the period between Marsh to September 2018. The patients were informed with the necessary information of the study. Study was approved by the research ethical committee of Faculty of Medicine, Zagazig University, and a written informed consent was obtained from all participants (patients included 63 males and 33 females patients with their age ranged from 46 and 75 years with a mean of 57.4 ± 6.8) . Conclusion: In the current study, we found highly significant positive correlation between admission heart rate and maximum high-sensitive troponin T level and Gensini score > 20 in the setting of NSTEMI. A significant positive correlation between age, male gender, QRS measurements, QTc dispersion, LVESD and Grace score and Gensini score > 20 was found in the setting of NSTEMI. There was a negative significant correlation between LVEF and Gensini score > 20.