Abstract
Background: The slight fluctuations in blood pressure (BP) regulation even without advancing to abnormal values appear to be related to more accelerated cardiovascular complications in patients with type 2 diabetes mellitus (T2DM). Morning blood pressure surge (MBPS) has been increasingly reported to provide a significant predictor of cardiovascular disease (CVD) risk.
Aim: To study the whether MBPS is associated with increased levels of microalbuminuria in normotensive T2DM patients.
Patients and methods: Normotensive T2DM patients were subjected to ambulatory blood pressure monitoring (ABPM) and urine spot sampling to assess urine albumin creatinine ratio (UACR).
Results: 32% of patients had microalbuminuria with a highly significant moderate positive correlation between UACR with DM duration, MBPS and average 2-hours systolic blood pressure (SBP) with (r = 0.342) p-value