Background: one of major adverse outcome of cardiac catheterization is acute kidney injury (AKI), and is associated with short-term and long-term mortality and morbidity .The pathogenesis of AKI is still not established although it is thought that the mechanism is medullary hypoxia lead to renal tubular dysfunction.
Objective: The aim of the study is to assess the efficacy of CHADS2 score in prediction of AKI in diabetic patients after percutaneous coronary intervention (PCI).
Methodology: This study was prospective cohort study done on 60 patients have diabetic history divided into two groups according CHADS2 score.
All diabetic patients underwent elective PCI.
All patients had the following: complete blood count, renal function, glycosylated hemoglobin (HbA1C), Resting electrocardiography, echocardiography Doppler study.
Serum creatinine was assessed before intervention, 48 hours after exposure to contrast media in PCI. Creatinine clearance was assessed also before and 48 hours after the intervention.
Results: AKI developed in eight patients ((13.3%) one patient with CHADS2 score < 3 and 7 patients have CHADS2 score >3.
The result showed that CHADS2 score is an independent predictor for incidence of AKI [odds ratio (OR) =8.111; 95% confidence interval (C.I) = 1.096 – 60.011; p=0.04].
There was a significant increase in AKI incidence with increased CHADS2 score
Conclusion: CHADS2 score is more accurate and sensitive in diagnosis of acute kidney injury after coronary intervention in comparison with old complicated scoring system.