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56252

LASER VERSUS RADIOTHERAPY IN THE TREATMENT OF EARLY GLOTTIC CARCINOMA

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Last updated: 22 Jan 2023

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Abstract

Background: Laryngeal cancer is one of the most common types of head and neck malignancy, although its optimal primary treatment is still a matter of debate. Methods: Typical patients with laryngeal SCC (90% at least) are males, over 45 years and heavy smokers. Hoarseness, voice changes, dysphagia, odynophagia, neck mass, dyspnea, referred otalgia and aspiration are the symptoms seen in laryngeal carcinoma. Glottic carcinomas are usually diagnosed earlier and hoarseness is the most common typical symptom. Results: All patients had completed the study. After comparison of the result between the 2 treatment groups, transoral laser excision shows better results than radiotherapy. There is significant difference between laser and radiotherapy in post-operative complications regarding granuloma tissue formation, tumor recurrence and web formation. In laser excision of laryngeal carcinoma, 10% of cases have post-operative granuloma while in radiotherapy, 66.6% of them have post-operative granuloma, but no cases has tumor recurrence while in radiotherapy, 33.3% of them have tumor recurrence. In laser excision of laryngeal carcinoma, 10% of cases have post-operative web formation while in radiotherapy, 22.3% of them have post-operative web formation. There is statistically significant difference between laser and radiotherapy in post-operative satisfaction about the voice (voice quality). Radiotherapy shows better results than laser in voice satisfaction. Conclusions: As regard the study, transoral laser excision of early glottic carcinoma shows better control rate and decrease recurrence and complications than radiotherapy.

DOI

10.21608/zumj.2019.10518.11060

Keywords

Laser, Radiotherapy, Cancer larynx, Glottic

Authors

First Name

Mohamed

Last Name

Mohamed

MiddleName

Abdel- Azim

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Orcid

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First Name

Alaa

Last Name

El-Fiky

MiddleName

Eldden

Affiliation

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Email

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City

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Orcid

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First Name

Abbas

Last Name

Sarhan

MiddleName

Mahmoud

Affiliation

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Email

abbas.sarhan@yahoo.com

City

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Orcid

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First Name

Wail

Last Name

Nasr

MiddleName

Fayez

Affiliation

-

Email

wail.fayez@yahoo.xom

City

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Orcid

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First Name

Mohamed

Last Name

Amin

MiddleName

Ahmed

Affiliation

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Email

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Volume

25

Article Issue

6

Related Issue

8434

Issue Date

2019-11-01

Receive Date

2019-10-31

Publish Date

2019-11-01

Page Start

941

Page End

949

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_56252.html

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https://zumj.journals.ekb.eg/service?article_code=56252

Order

18

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

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Article

Created At

22 Jan 2023