The crucial care placing desires early checks which permit clinicians to properly stratify patient hazard, to diagnose organ disorder early, and to set a focused remedy speedy. This raises the idea of biomarkers. An excellent biomarker check have to be secure, clean to perform, as non-invasive as viable, completed at the bedside or with a (quite) easy laboratory test, speedy, distinctly precise for the sickness, its subtypes and reasons, and touchy for as early detection as feasible. Biomarker checks were categorized clinically into: precursor, screening, indicative, stage, and predictive. Biomarker assessments can also contain measurements immediately on organic media or measurements which include brain imaging which do not contain direct sampling of organic media however measures modifications inside the composition or feature of the nervous system. The biomarkers mentioned in this article are biomarkers of cardiovascular illnesses, breathing illnesses, renal illnesses , as well as biomarkers of disorders of the nervous system , biomarkers of infection and biomarkers of gastrointestinal illnesses. A panel of biomarkers appears to be a probable answer for accomplishing a whole affected person assessment together with a good enough medical evaluation and tracking.