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28196

ASSESSMENT OF DIFFERENT NON-INVASIVE SCORE MODALITIES IN PREDICTION OF ESOPHAGEAL VARICES IN PATIENTS WITH LIVER CIRRHOSIS

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Last updated: 22 Jan 2023

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Abstract

Background:  Varices are a serious consequence of portal hypertension, and variceal bleeding is a life-threatening complication occurring in up to 30% of patients with cirrhosis. Despite the great improvement in diagnosis and the available therapeutic modalities, mortality from acute variceal bleeding may still reach up to 20%. Therefore, our aim was to assess the role of non-invasive score modalities in the prediction of the presence of EVs & to predict EVs severity. Methods: This Comparative cross-sectional study was conducted on a cohort of 90 cirrhotic patients. All patients were subjected to investigations include complete blood count, liver and kidney function tests, bleeding profile, random blood sugar, and serum sodium.The following scores were estimated: Child-Pugh score, MELD -Na+ score, AAR, APRI, FIB-4, and King's score. Upper GI endoscopy was done for evaluation of presence or absence of EVs. Results: Our results revealed that Kings Score is the most sensitive and specific score in predicting the presence of EVs, followed by APRI score while AAR score has the least sensitivity and specificity.FIB-4 score is the most sensitive scoring system in predicting severe EVs, followed by APRI, Kings, and AAR scores. Regarding specificity, King's Score is the most specific one followed by FIB-4, APRI and AAR. Conclusions: King's score has the highest sensitivity and specificity in EVs prediction followed by APRI. Regarding severe EVs, FIB-4 score is the most sensitive scoring system in the prediction of severe EVs. However, King's score is the most specific one.  

DOI

10.21608/ZUMJ.2019.27411

Keywords

Esophageal varices, GIT Endoscopy, Cirrhosis, Non-Invasive modalities

Authors

First Name

Kamel

Last Name

A. Ahmed

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First Name

Ibrahim

Last Name

H. Mohammed

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First Name

Farag

Last Name

Alaa

MiddleName

A.

Affiliation

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First Name

Gomaa

Last Name

Ahmed

MiddleName

F.

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Volume

25

Article Issue

2

Related Issue

5034

Issue Date

2019-03-01

Receive Date

2019-03-01

Publish Date

2019-03-01

Page Start

261

Page End

268

Print ISSN

1110-1431

Online ISSN

2357-0717

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https://zumj.journals.ekb.eg/article_28196.html

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https://zumj.journals.ekb.eg/service?article_code=28196

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9

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Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

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Article

Created At

22 Jan 2023