Beta
28193

IMPACT OF INFARCT RELATED ARTERY AND ITS PATENCY ON THE OUTCOMES OF PATIENTS UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

-

Abstract

Background: Primary percutaneous coronary intervention (PCI) for acute myocardial infarction might be associated with suboptimal coronary flow with consequent poor functional recovery and higher rate of complications. Identification of the predictors of reperfusion failure can increase the rate of procedural success, preserve ventricular function and lessen mortality. We aimed to find the association between baseline coronary patency & culprit site with PCI outcome and the incidence of major adverse cardiac events (MACE). Methods: 46 STEMI patients treated by primary angioplasty were enrolled, then grouped according to the infarction related artery patency graded by TIMI flow. Over the next 3 months, patients were followed for the incidence of stent thrombosis, re-infarction, acute decompensated HF & death. Results: 27 patients had initial TIMI 0 flow and 19 patients had initial TIMI ≥1 flow.The proportion of satisfactory PCI outcome was 44.4% and 78.9% respectively (p=0.019). The later incidence of MACE was 66.7% and 21.1% respectively (p=0.002). The culprit vessel was LAD, LCX and RCA in 54.3%, 10.9% and 34.8% of the cases. When grouped based on the culprit, incidence of MACE was 68%, 20% and 25% (p=0.011). Multivariate logistic regression analysis found that initial TIMI 0 flow (p=0.013) and LAD as the infarction related vessel (p=0.032) were independent predictors for MACE. Conclusion: Initial infarction related artery patency at angiography has a direct impact on PCI outcome. Baseline TIMI 0 flow and LAD as a culprit site are independent predictors for major adverse cardiac events in STEMI patients undergoing primary angioplasty.    

DOI

10.21608/ZUMJ.2019.27409

Keywords

STEMI, Primary PCI, TIMI flow, LAD, MACE

Authors

First Name

Mohammad

Last Name

Alameddin

MiddleName

Ibrahim

Affiliation

-

Email

m3alamdien@gmail.com

City

-

Orcid

0000-0002-3465-7508

First Name

Mesbah

Last Name

Hasanin

MiddleName

Taha

Affiliation

-

Email

mesbahhasanein1@gmail.com

City

-

Orcid

-

First Name

Tamer

Last Name

Mostaf

MiddleName

Mohamed

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Wael

Last Name

Khalil

MiddleName

Ali

Affiliation

-

Email

drwael123456@yahoo.com

City

-

Orcid

-

Volume

25

Article Issue

2

Related Issue

5034

Issue Date

2019-03-01

Receive Date

2019-03-01

Publish Date

2019-03-01

Page Start

234

Page End

241

Print ISSN

1110-1431

Online ISSN

2357-0717

Link

https://zumj.journals.ekb.eg/article_28193.html

Detail API

https://zumj.journals.ekb.eg/service?article_code=28193

Order

6

Type

Original Article

Type Code

273

Publication Type

Journal

Publication Title

Zagazig University Medical Journal

Publication Link

https://zumj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023