Bachground: Cholelithiasis is one of the most common disorders of the digestive tract encountered by
general surgeons worldwide. Conventional or open cholecystectomy was the mainstay of treatment for a long
time for this disease. Laparoscopic cholecystectomy (LC) has been the gold standard for removal of the
gallbladder since the early 1990s. Single-incision laparoscopic surgery is becoming a more widely accepted
surgical approach. However, the feasibility and safety of single-incision laparoscopic cholecystectomy (SILC)
are yet to be established. The present study compared outcomes following the use of SILC or conventional
laparoscopic cholecystectomy (CLC) on patients with gallbladder disease.Aim: To compare the perioperative
results of single port laparoscopic cholecystectomy with the standard 4-port technique.Subjects and methods:
The study involved 72 symptomatic gallbladder disease patients underwent laparoscopic cholecystectomy in
Zagazig University hospital.36 patients underwent SILC, and 36 patients underwent CLC. Clinical and surgical
outcomes were compared.Results: The SILC and CLC groups were similar in terms of age, gender ratio, body
mass index, and diagnoses. The two groups were also found to be similar in terms of postoperative clinical
course and complications. The SILC group had a longer operation time, less postoperative pain, and a shorter
hospital stay with better aesthetic results than the CLC group.Conclusion: SILC was as safe and feasible as
CLC. The operating time was longer otherwise it has almost similar clinical outcomes to those of CLC.
Keywords: Four port technique, Laparoscopic surgery, Single port surgery