Abstract Background: The lower urinary tract symptoms (LUTS) have become very common among adult men. They encompass a variety of storage, voiding, and post-micturition symptoms. Aim of Study: To determine bladder wall thickness in healthy adult men in correlation with uro-flowmetry to assess its feasibility in diagnosing Bladder outlet obstruction (BOO) in male patients with lower urinary tract symptoms. Patients and Methods: The present study was conducted on 75 patients with lower urinary tract symptoms and aging more than 18 years old, admitted through the outpatient clinic of Urology in Ain Shams University Hospitals and Ahmed Maher Teaching Hospital through the period from 1/2020 to 10/2020. Results: Median of Bladder wall thickness (BWT) the non-obstructed patients is 2 (1.7-2.55) and range 1.4-6.5 and the median BWT in the obstructed patients is 7 (6-7.9) and range 2.5-8.8. We found that the cutoff value of 3.9mm for BWT (mainly detrusal) was found to be the best threshold value to distinguish patients with BOO from those without bladder outlet obstruction. The patients were divided into an outlet obstruction group and non-outlet obstruction according to their Qmax. The obstructed group is below Qmax 10 and the non-obstructed above Qmax 10. Conclusion: USG measurements of BWTare useful in the diagnosisof symptomatic BOO. Moreover, the easy measure-ment of BWT, by suprapubic USG makes these parameters acceptable to bothpatients and physicians, and can be used for routine clinicalevaluation of patients with symptomatic BOO.