Abstract Background: Postmenopausal bleeding is vaginal bleeding that occurring after one years of menopause. When periods have stopped for more than one years in women who are generally over than 45 years old and it is common condition in postmenopausal women ; it can be the presenting symptom of endometrial cancer. Aim of Study: To assess endometrial thickness by vaginal sonography and correlate it with the cytological pattern evaluated by endometrial sampling and histopatho logical typing of the endometrium. Patients and Methods: This study was conducted at Obstetrics and Gynecology unit in Bab-Al Sharia University Hospital and Al-Moniera General Hospital from September 2018 to August 2019. The study included 100 patients com-plaining of postmenopausal bleeding at the outpatient clinic. Results: ET ³10 has a sensitivity of 96.1% specificity of 92.3% positive predictive value of 66.3%, negative predictive value of 97% with diagnostic area under the curve of 0.878 in detection of endometrial disorders. Conclusion: TVS evaluation of ET and uterine size is a reliable method of screening postmenopausal women with PMP. No abnormal endometrium detected in postmenopausal women with endometrial thickness less than 4mm and all causes of endometrial carceinoma have endometrial thickness more than 9mm.