Abstract Background: Stroke is one of the leading causes of death and long-term disability worldwide. Aim of Study: This study aimed to conduct the effect of selected exercise programe on quality of life in stroke patients. Material and Methods: Ten male patients with stroke enrolled in this study. A selected physical therapy program was provided for the selected group (GS) including: Passive Range of motion exercises for tightening muscles, Facilitation for weak muscles through: PNF technique, quick stretching. The Outcome Measures: The Arabic version of a short form dimension test (SF-36) used to assess the QOL Items of the SF-36 were divided into eight different domains. The control group was evaluated before and after intervention with a QOL questionnaire (SF36). Results: There was a revealed significant increase in physical functioning, energy/fatigue, emotional well-being, social functioning, pain and general health post treatment compared with that pretreatment. Also, there was no significant difference in role limitations due to physical health and role limitations due to emotional problem between pre and post treatment in the selected group. Conclusion: Selected physical program, significantly improves quality of life in patients with stroke.