Abstract Background: Several studies compared right to left sided colon cancers, the conclusion was that right-sided tumors carry a worse prognosis than left-sided ones, and even some authors went more in considering them two distinct tumors that should be treated in a different manner. Aim of Study: The aim of this study was to delineate colorectal cancer age and sex distribution, pathologic pattern at time of resection of cases admitted to Nasser Institute Hospital in the period between Jan. 2018 and Dec. 2019. Patients and Methods: This is a retrospective study con-ducted at histopathology department of Ain Shams University hospital by collecting the data from histopathological reports of 114 patients who underwent surgical resection of colorectal cancers in colorectal unit in Nasser Institute Hospital during the period from Jan. 2018 to Dec. 2019. Results: This study included 86 patients who underwent any type of colorectal resection for their malignant lesion and underwent pathological assessment for their excised specimens in Nasser Institute Hospital in the period between January 2018 and December 2019. Totally 114 patients underwent colorectal resections in this period, Benign tumors were found in 28 patients out of 114 (25%), while malignant tumors were found in 86 out of 114 (75%).