Abstract Background: Most of thalamic tumors are low grade. They have critical anatomical position especially in children's due to adjacent to important structures. The Aim Study: Is to present the authors' experience in the management of 24 cases of pediatric thalamic low grade tumors. Patients and Methods: Medical records of 24 pediatric patients with thalamic brain tumors admitted to Children Cancer Hospital during the period from July, 2007 till Decem-ber, 2014 have been reviewed as regard surgical interference, and chemo-therapy in relevance to tumor size, patients' age, different histopathological subtypes, and patients' presenting symptoms. Conclusion: Most of thalamic brain tumors are low grade tumors with significant level of morbidity and mortality that require integrated analysis of further studies to achieve better outcome.