AbstractBackground: Acute Appendicitis (AA) can be consideredthe signature disease encountered by the general surgeon. Itis the most frequent abdominal diagnosis treated by surgeons.There have been numerous previous studies comparing OpenAppendectomy (OA) with Laparoscopic Appendectomy (LA).Although most of these have concluded that the laparoscopictechnique is as good as OA, there has been considerablecontroversy as to whether LA is superior to OA or not.Aim of Study: The aim of this study is to compare betweenlaparoscopic and open appendectomy regarding operativetime, post-operative pain, complications, time to return tousual activity and cosmesis.Patients and Methods: We included 40 consecutive patientswith acute appendicitis. The patients were randomly allocatedinto 2 groups; 20 patients for Laparoscopic Appendectomy (LA) group and 20 patients for Open Appendectomy (OA)group. Patients were fully informed about the risks and benefitsof the two procedures. Informed consent was obtained fromall patients. LA was done with the help of three trocar/cannulaecreating pneumoperitoneum with CO2 whereas OA was per-formed by McBurney incision.Results: The operating time in OA group was (34.50±11.48min.) with range (20-60min.) and in LA group it was (56.42± 8.69min.) with range (30-70min.). LA is safe and had majorbenefits like less operative time, less post-operative pain,decreased wound infection, short hospital stay, early returnto work and a better cosmetic scar than OA.Conclusion: Laparoscopic appendectomy is safe andfeasible. Despite that the operating time for laparoscopicappendectomy is still longer than that for open appendectomy,laparoscopic approach had several advantages over openappendectomy in that, it has less incidence of wound infection,shorter hospital stay, less incidence of severe post-operativepain and faster return of patients to normal activities and moresatisfying cosmetic results. We must convert laparoscopicprocedure to open surgery when indicated for the safety ofthe patients.