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125463

Value of Diffusion Weighted Magnetic Resonance Imaging in Diagnosis of Cervical Carcinoma

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Last updated: 22 Jan 2023

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Abstract

Abstract Background: Carcinoma of the uterine cervix is the third most frequently diagnosed malignancy in women worldwide. It remains a leading cause of cancer-related death for women in developing countries. Conventional MRI has an established role in gynecologic imaging. However, increasing clinical demand for improved lesion characterization and disease mapping to optimize patient management has resulted in the incorporation of newer sequences, such as diffusion-weighted imaging (DWI). Aim of Study: The aim of this study is to evaluate the role of DW-MRI in the diagnosis of cervical carcinoma. Patients and Methods: This is a descriptive exploratory (case-series) study that included 20 female patients diagnosed with cervical cancer, Pelvic MR, DWI and DCE- MR were done for all patient. The study was conducted in El-Demerdash Hospital from March 2019 – Feb. 2020. Results: This study group consisted of 20 female patients diagnosed with cancer cervix, Pelvic MR with DWI and DCE-MR were done for all patients. Lesions in all cases were seen restricted on DWI (high signal intensity in DWI with low ADC map) with hetrogenous patterns was seen in (17/20, 85%) cases, homogenous patterns was seen in (2/20, 10%) and mural pattern in (1/20,5%) case. All lesions showed low ADC maps from 0.6 to 1.2 (x10-3mm2/sec), <0.8 x10-3mm2/ sec was seen in 5 cases (25%) and ³0.8 x10-3mm2/sec was seen in 15 cases (75%). A total 20 cervical cancer lesions, 5 lesions were stage IIA (25%), 10 lesions were stage IIB(10%), 4 lesions were stage IVA (20%) and 1 lesion was stage IVB (5%) of figo classification. Conclusion: DWI is a potentially useful adjunct to con-ventional MRI in the evaluation of gynecologic tumors, thus improving the overall diagnostic accuracy, tumor staging.

DOI

10.21608/mjcu.2020.125463

Keywords

MRI, DW-MRI, Cervical Cancer

Authors

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NORHAN A. HELMY, M.Sc.;

Last Name

MARWA A. EL-SAYED, M.D.

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NAGLAA

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SHEBRYA, M.D.

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Affiliation

The Department of Radiodiagnosis, Faculty of Medicine, Ain Shams University

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Volume

88

Article Issue

December

Related Issue

14148

Issue Date

2020-12-01

Receive Date

2020-09-25

Publish Date

2020-12-01

Page Start

2,311

Page End

2,319

Print ISSN

0045-3803

Online ISSN

2536-9806

Link

https://mjcu.journals.ekb.eg/article_125463.html

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https://mjcu.journals.ekb.eg/service?article_code=125463

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40

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Original Article

Type Code

263

Publication Type

Journal

Publication Title

The Medical Journal of Cairo University

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https://mjcu.journals.ekb.eg/

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Article

Created At

22 Jan 2023