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116240

The Use of Botulinum Toxin as an Adjuvant in Managing Children with Chronic Constipation and Obstructed Defecation

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Last updated: 22 Jan 2023

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Abstract

Abstract Background: Pediatric chronic constipation and obstructed defecation is a challenging problem, with bad impact on quality of life affecting both the child and family. It is a complex disorder of multifactorial etiology and pathophysi-ology. Many symptoms-based systems have been instructed for clarifying definitions for chronic constipation and obstruct-ed defecation such as ROME IV criteria, PACCT criteria, NICE guideline. Most protocols of management of functional constipation usually include; disimpaction enemas, feeding regulations, bowel diaries and laxatives. Aim of Study: To evaluate the effectiveness of adding anal Botox injection to those already following management plan for pediatric age group suffering from chronic constipation and obstructed defecation. Patients and Methods: The current study included 40 children with functional constipation, and obstructed defeca-tion. The study started in April 2017 and completed the patients follow-up in November 2019. Bowel management program was applied with Botulinum toxin injection. Patients were followed-up at 2 months, and 6 months using Rintala Scores. Results: The study included 45% female members and 55% male ones, with age range between 3-12 years. Improve-ment was achieved in 22.5% of children after 2 months of the management, all patients were followed-up at least for 6 months period, with a mean follow-up of 11.35 months. Rintala scores at initial presentation, 2 months and 6 months follow-up showed improvement. Overall, across all the study subjects, females did better and showed more improvement. Conclusion: This study has confirmed that BT injection did not add any significant effect, to children with obstructed defecation and chronic FC.

DOI

10.21608/mjcu.2020.116240

Keywords

Pediatric constipation, chronic constipation, Functional constipation, Obstructed defecation, Anal sphincteric Botox injection

Authors

First Name

AYMAN A. TALAAT, M.D.;

Last Name

AYMAN A. ALBAGHDADY, M.D.

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AHMED B. ARAFA, M.D.;

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MOHAMMAD R. EL-SHAHAWY, M.Sc.

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Affiliation

The Departments of General Surgery* and Pediatric Surgery**, Faculty of Medicine, Ain Shams University

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Volume

88

Article Issue

September

Related Issue

14147

Issue Date

2020-09-01

Receive Date

2020-06-30

Publish Date

2020-09-01

Page Start

1,503

Page End

1,506

Print ISSN

0045-3803

Online ISSN

2536-9806

Link

https://mjcu.journals.ekb.eg/article_116240.html

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https://mjcu.journals.ekb.eg/service?article_code=116240

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8

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Original Article

Type Code

263

Publication Type

Journal

Publication Title

The Medical Journal of Cairo University

Publication Link

https://mjcu.journals.ekb.eg/

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Article

Created At

22 Jan 2023