Abstract Background: Gynandriris sisyrinchium is a traditionally used medicinal plant, yet there is no enough information about its phytochemical profile. In this endeavour. Aim of Study: We aimed to carry out a detailed phyto-chemical screening of the active constituents in the bulbs, stems, leaves and flowers of Gynandriris sisyrinchium growing wild in Kuwait. Material and Methods: Phytochemical screening were done for plant after collection from Kabd Area in Kuwait during March 2005. Results: The present study results reported moderate presence of cardiac glycosides, carbohydrates and saponins in the bulbs, while Flavonoides are more in the aerial parts. Triterpenes and sterols are present in slight quantities. Also it's clear that the plant is devoid of Alkaloids and Anthraqui-nones. Conclusion: The results of the current paper could serve as a starting point for further future investigation of the contents of the Gynandriris syrinchium plant.