110931

Evaluation of Nutritional Status as a Prognostic Indicator for the Outcome in Liver Transplant Recipients

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Last updated: 01 Jan 2025

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Abstract

Abstract Background: Mal-nutrition is a common complication of the end-stage liver disease and associated with increased morbidity and mortality rates. Numerous studies have proved that pre-operative mal-nutrition is related to higher risk of surgical morbidities and mortalities in general surgical patients. Mal-nourished patients tend to have high rates of infectious complications, prolonged intensive care unit (ICU) stay, hospital stay and increased mortality. Aim of Study: To determine the impact of nutritional status pre-liver transplant on recipients' course and the outcome post-transplant. Patients and Methods: Pre-operative nutritional assessment with Subjective global assessment (SGA) was done retrospec-tively for 52 patients, categorized as well-nourished, mild, moderate and severe mal-nourished and followed for post-operative course. Results: The causes of transplant were mainly decompen-sated chronic liver disease (46.2%), hepato-cellular carcinoma (32.7%) and auto-immune with HCC (11.5%). As a result of all these complications, the ICU stay, hospital stay, 28 day mortality were less in well-nourished patients in comparison to the mal-nourished one. Conclusion: The nutritional status pre-liver transplant is an important factor which can affect the outcome of the liver transplant patients. The mal-nourished patients showed a higher incidence of post-operative sepsis, a higher post-operative bilirubin levels, a more need for post-operative nutritional intervention, a higher incidence of need of re-intubation for mechanical ventilation, a higher incidence of post-operative renal impairment and neurological complica-tions. As a result of all these complications, the ICU stay, hospital stay, 28 day mortality were less in well-nourished patients in comparison to the mal-nourished one. So, pre-operative assessment and optimizing the nutritional status is an essential step before proceeding for surgery.

DOI

10.21608/mjcu.2020.110931

Keywords

Malnutrition, Mal-nourished, Well-nourished, Liver transplantation, SGA, HCC, Decom-pansated chronic liver disease, TPN, Demo-graphic data, BMI, Post-operative, Nutritional intervention, stay, mortality, Liver functions, Sepsis, renal

Authors

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MOHAMED A.M. ALI, M.D.;

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RANDA A. SHOUKRY, M.D.

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DALIA F. EMAM, M.D.;

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EMAN I. EL-DESOKI MAHMOUD, M.D.

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First Name

MOHAMED I.I.

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AKP EL-BAB, M.Sc.

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Affiliation

The Department of Anesthesiology, General Intensive Care Medicine & Pain Management, Faculty of Medicine, Ain Shams University* and Fellow of General Intensive Care, National Hepatology & Tropical Medicine Research Institute, Cairo**

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Volume

88

Article Issue

June

Related Issue

14146

Issue Date

2020-06-01

Receive Date

2020-01-04

Publish Date

2020-06-01

Page Start

1,287

Page End

1,295

Print ISSN

0045-3803

Online ISSN

2536-9806

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https://mjcu.journals.ekb.eg/article_110931.html

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https://mjcu.journals.ekb.eg/service?article_code=110931

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37

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Original Article

Type Code

263

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The Medical Journal of Cairo University

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https://mjcu.journals.ekb.eg/

MainTitle

Evaluation of Nutritional Status as a Prognostic Indicator for the Outcome in Liver Transplant Recipients

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Article

Created At

22 Jan 2023