Abstract Background: Hepatic transplantation especially from living donors has allowed widespread utilization of the pro-cedure in management of terminal hepatic disease. Complications following hepatic transplantation are en-countered frequently. These complications may be either vascular or non-vascular complications. The non-vascular complications may include, biliary complications, infection and tumoral recurrence. Different diagnostic radiological procedures are used for identification of these complications including ultrasound, Doppler, computed tomography and magnetic resonance imaging. Recent advances in multislice computed tomography including the multiplanar and angiographic capabilities have expanded the role of computed tomography in the identification and differentiation of such complications. Aim of Study: The aim of this study is to highlight the importance of multi-slice CT in the identification and evalu-ation of the various non-vascular post-operative complications in recipients following hepatic transplantation. Patients and Methods: This is a prospective study that included 45 patients presenting with suspected post hepatic transplantation complications. Patients were referred to the Kasr Al-Aini Hospital Radiology Department between October 2017 to December 2019 to perform Multislice CT (MSCT) for further evaluation of underlying complications. Results: Non-vascular complications were found in 21 cases (46.6%). Biliary complications represented 57.1% of the non-vascular complications (7 cases biloma and 5 cases biliary stricture). Parenchymal complication included 2 cases of hepatic abscess (9.5%) and 2 cases of graft rejection (9.5%). Neoplastic complications included 4 cases recurrent HCC (19%) and 1 case neoplastic lympho-proliferative disorder (4.7%). Conclusion: MSCT of the liver is a feasible non-invasive procedure for evaluating non-vascular complications following liver transplantation allowing prompt and proper intervention.