Abstract Background: Asthma and wheezes are the most common acute and chronic diseases in childhood. Early detection and good management of asthma is very important to reduce the risk and improve the health status of the diseased children. Aim of Study: Is estimation of asthma prevalence among school-aged children at Elmaraghah Center in Sohag Gover-norate, also to identify the role of different risk factors associated in aetiology of asthma. Patients and Methods: This cross sectional survey study, was conducted on 1796 children, (897 males and 899 females) from six to twelve years old in public primary schools in Elmaraghah center in Sohag governorate, all patient groups were exposed to questionnaire adopted from (ISAAC). Results: The prevalence of asthma between children included in the current study was (12.5%). Atopic dermatitis, food allergy, drug allergy, passive smoking and family history were related to high prevalence of bronchial asthma. Conclusion: The prevalence of asthma was 12.5%, and allergy to food and drugs is the most important risk factor of bronchial asthma.