Abstract Background: Recurrence of ischemic symptoms after coronary artery bypass graft surgery requires imaging assess-ment of bypass graft lumen to rule-out graft dysfunction. Aim of Study: Is to evaluate the role of 320-row multide-tector CT as a non-invasive imaging modality for assessment of coronary artery bypass grafts. Results: Twenty one patients were referred to assess the patency of coronary artery bypass grafts. All patients were subjected to history taking, clinical examination as well as CT angiography of coronary arteries and coronary artery bypass grafts using 320-row multidetector CT scanner after heart rate control and injection of non-ionic contrast material. Total number of 63 interpretable coronary artery bypass grafts were included in this study. On evaluating 23 arterial grafts, all of LIMA grafts were patent without stenosis except for LIMA to D2 graft which shows subtotal distal anastomotic site occlusion. The only RIMA graft in this study was occluded whereas radial artery graft to OM was patent. On evaluating 40 venous grafts, 11 (27.5%) grafts were considered patent, 3 (7.5%) grafts showed significant (>!50) stenosis and 26 (65%) grafts were occluded. Conclusion: Multidetector CT is considered convenient and reliable non-invasive imaging modality for assessment of suspected graft dysfunction.