Abstract Background: Maxillofacial fractures are common and must be radiologically evaluated to detect fractures, to deter-mine their morphology and topography, and to assess adjacent soft-tissue damage. Aim of Study: The aim of the current study was to evaluate the role of MDCT in diagnosis of: Maxillofacial fractures. Patients and Methods: This prospective cross-sectional study was carried in Radiodiagnosis Department, Zagazig University Hospitals and private center on twenty eight patients complaining from facial trauma with suspected facial fractures referred from Emergency Department, they were 22 males and 6 females, a ages ranged from 17 to 51 years with mean age of 29 years old. Conventional plain radiography and MDCT were performed to all patients. Results: MDCT examination showed that the most com-mon simple maxillofacial fracture was orbital wall fracture (7 patients), the most common complex fractures zygomatico-maxillary complex fracture (5 patients), the most common orbital bony wall fracture was orbital floor fracture (8 patients). Conclusion: MDCT is the optimal imaging modality for evaluation of maxillofacial fractures, as it can be often visualize complex injuries with a precision unattainable by conventional radiography or clinical examination. Fracture fragments displacement and rotation are easily determined by MDCT and 3D MDCT is the best modality for demonstrating the spatial relationships of fracture fragments in maxillofacial fractures.