Abstract Background: Female sexual dysfunction (FSD) is charac-terised by disturbances in sexual desire and psycho-physiological changes associated with the sexual response cycle. Female sexual dysfunction (FSD) is defined as disorders of libido, arousal, orgasm, and sexual pain that lead to personal distress or interpersonal difficulties. It is a common problem, affecting 30-78% of women. Aim of Study: Was to report the epidemiologic aspects of female sexual dysfunction in Delta of Egypt. Patients and Methods: This study was designed as a cross-sectional one and conducted on married women attending urology and/or gynecology outpatient clinic in Delta of Egypt mainly Tanta University Hospitals; between April 2017 and October 2018. Counseling was performed to explain the goals, steps and security of information of the study with 2822 attending married women to outpatient clinics, 310 women refused to share in the. The response rate was 89%. The number of included women in the study was 2512. Results: Based on the total sexual function score, 1455 (57.9%) had sexual complaints (group A) while 1057 women (42.1 %) had no sexual disturbance (group B). The total score of FSFI ranged from 4.6 to 25.7 in group A (mean=) and from 27.3 to 35.1 in group B (mean=). (p=0.001) Comparison of the individual domain scores showed that women in the sexual dysfunction group had significantly lower scores in all domains as compared to those without sexual dysfunction (p=0.001). Conclusion: Female sexual dysfunction is highly prevalent problem but underestimated due to cultural, religious factors, lack of awareness and information about sex.