Abstract
Background: Gastritis: Defines any (histologically con-firmed) inflammation of the gastric mucosa. Worldwide, the epidemiology of gastritis overlaps that of Helicobacter pylori infection, which affects approximately 50% of the world's population. The aim of the current study was to investigate the value of I-scan in diagnosis gastritis whether HP positive or negative.
Subjects and Methods: This study included 164 patients divided into three groups. Group (1) included 12 normal subjects, Group (2) 101 helicobacter pylori positive subjects with gastritis and Group (3) 51 helicobacter pylori negative subjects gastritis. Upper endoscopy was performed for all cases, first by WLE then we shifted to I scan technology. Two biopsies were taken, one from greater curvature of the body of stomach and the other from antrum). All patients were assessed clinically, biochemically, viral markers and by ultrasound.
Results: In the helicobacter pylori positive gastritis we found that absence of collecting venule and Subepithelial Capillary Net Work (SECN) had good sensitivity 93% and poor specificity 32%.
Conclusion: I scan has poor specificity in diagnosis of HP gastritis.