Statement of the problem:
Preservation of the gingival health of the abutment is one of the most important factors for overdenture success. Many investigators modify acrylic resin to improve the biocompatibility.

Objective:
The aim of this study was to assess the effect of Titanium dioxide nanoparticles incorporation in acrylic resin overdenture on the gingival health of the abutment.

Materials and methods:
Twelve patients with remaining two mandibular canines were selected and divided randomly into two groups. Group 1 patients received Mandibular overdenture constructed with Titanium dioxide nanoparticles incorporated in the acrylic resin. Group 2 patients received mandibular overdenture constructed with conventional acrylic resin.
All patients were scheduled for recall visits at 2,4,6 and 8 weeks after delivery. Four points around each abutment were recorded for the plaque index, gingival index and gingival bleeding index.

Results:
As regards the plaque index scores , gingival index and gingival bleeding index scores there was an increase in both groups of patients. The increase was statistically significant in group 2 and non significant in group 1.

Conclusion:
Within the limitations of this study, tooth supported overdenture constructed with acrylic resin with Titanium dioxide nanoparticles strengthened the gingival health of the overdenture abutments than the conventional acrylic resin.