Introduction: The purpose of this retrospective study was to assess the outcome of endodontic retreatment performed in single visit. Methods: Retreatments were identified from the pool of patients treated in Dubai Health Authority (DHA) endodontic clinics between 2018 and 2019. The cases included were retreated in a single visit and followed up for at least 6 months. Data were retrieved from 139 cases and a template was created to collect demographic, procedural, clinical and radiographic information. Short term flare up and long term clinical and radiographic outcome were assessed, in addition to calculation of tooth survival. Moreover, the preoperative apical status and quality of root canal filling were studied as prognostic factors and were analyzed for their impact on the outcome. Results: Data from 127 patients, where 99 cases from women and 40 cases from men with a mean age of 46.5 years, showed that flare up occurred in 2.9% of the cases; a success rate of 92.1 % and survival rate of 94%. Statistical analysis did not discern an association between the quality of the previous root canal filling and outcome of retreatment. Conversely, there was an association between the presence of a preoperative apical periodontitis and outcome of treatment (p= 0.006) Conclusion: Single visit endodontic retreatment performed by specialists on asymptomatic teeth is a predictable therapy with a high incidence of healing and tooth retention.