Purpose: investigating the effect of insulin and metformin on the prevalence and severity of tooth wear in patients with type 2 diabetes.
Patients and methods: this cross sectional study was conducted on194 Egyptian adult diabetic type 2 patients, age group (50-70) using quota sampling method, assessing the prevalence and severity of tooth wear in adults of the included region. Three-stage stratification was done by sex, age and type of diabetes, then classified in to two groups: Group A: 105 patients treated with insulin regimens without metformin and stop metformin at least 5 years ago. Group B: 89 patients treated with metformin only. Measuring the tooth wear by Smith and Knight Tooth Wear Index (TWI).
Results: Teeth Wear index (TWI) was significantly positively correlated to age and duration of diabetes in all groups. Treatment with metformin was a significant positive predictor of TWI. TWI was 1.857 higher on average for those who use metformin as compared to those who use insulin.
Conclusion: There was a significant difference between different TWI as regard age and duration of diabetes. Any factor changes the oral salivary PH and viscosity will affect on the tooth wear severity.
Keywords: type2 diabetes, tooth wear, insulin, metformin, tooth wear index