Objectives: The objective of this research is to investigate the antibacterial effect of mixing 2% Chlorhexidine with Calcium hydroxide or Triple antibiotic paste intracanal medicaments.
Materials and Methods: Forty-five single rooted primary teeth were utilized in this study, after the basic chemico-mechanical root cleaning, the roots were sorted randomly into four groups (I- IV) according to the intra-canal medicament used such that; Group I: calcium hydroxide, Group II: triple antibiotic paste, Group III: calcium hydroxide in a 2% chlorhexidine solution and lastly Group IV: triple antibiotic paste in a 2% chlorhexidine solution.
Results: The least antibacterial effect was observed in the pure calcium hydroxide group, the antibacterial effect of calcium hydroxide and triple antibiotic paste is enhanced when mixing the powder components in chlorhexidine solution instead of distilled water, yet the increase of the antibacterial activity is not statistically significant.
Conclusions: Multidrug intracanal medicaments are more effective than single drug medicaments to counteract resistant bacteria in necrotic root canals of primary teeth, in addition chlorhexidine appears to be a viable vehicle for calcium hydroxide and triple antibiotic paste.