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227319

The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study)

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pediatric & Preventive Dentistry

Abstract

Background: Eugenol is a frequent component of dental biomaterials and is known to exhibit a range of antimicrobial activity. However, there is a lack of reports on evaluating the antimicrobial activity of eugenol versus chlorhexidine on oral lactobacilli. Material and methods: In the current study, we evaluated the in vitro antimicrobial activity of eugenol by agar diffusion method on 15 Lactobacillus isolates initially isolated from pre-school children and compared the efficacy of eugenol with chlorhexidine. Results: the study showed inhibition zones of eugenol ranged from 6 to 10 mm, while those of chlorhexidine ranged from 7 to 11mm. The statistical analysis using paired t-test revealed a significant difference (P < 0.001) for eugenol and chlorhexidine groups with respect to their antimicrobial efficacy against oral lactobacilli. The minimum inhibitory concentration of eugenol and chlorhexidine were 100-400 and 20-40 micro gm/ml, respectively. Conclusion: The effectiveness of eugenol against lactobacilli was promising in inhibiting caries

DOI

10.21608/edj.2022.110223.1900

Keywords

Antimicrobial, chlorhexidine, early childhood caries, eugenol, Lactobacilli

Authors

First Name

Rehab Samir

Last Name

Salma

MiddleName

-

Affiliation

Department of Pediatric Dentistry, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

Email

rehab_samir@yahoo.com

City

Alexandria

Orcid

0000-0002-4702-1947

First Name

Moustafa A

Last Name

Matar

MiddleName

-

Affiliation

Department of Pediatric Dentistry, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

Email

moustafa.matar@pua.edu.eg

City

-

Orcid

0000-0003-3709-9246

First Name

Sherif S

Last Name

Darwish

MiddleName

-

Affiliation

Department of Pediatric Dentistry, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

Email

sherif.darwish@pua.edu.eg

City

-

Orcid

0000-0003-2147-6203

First Name

Nader

Last Name

Elseoudy

MiddleName

A.

Affiliation

Senior Student, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

Email

-

City

-

Orcid

-

First Name

Moustafa

Last Name

Kandil

MiddleName

A.

Affiliation

Senior Student, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

Email

-

City

-

Orcid

-

First Name

Mohab

Last Name

Mehelba

MiddleName

H.

Affiliation

Senior Student, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

Email

-

City

-

Orcid

-

First Name

Walid A

Last Name

Lotfy

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt

Email

walid.lotfy@pua.edu.eg

City

-

Orcid

0000-0001-5777-4275

Volume

68

Article Issue

2

Related Issue

32592

Issue Date

2022-04-01

Receive Date

2021-12-09

Publish Date

2022-04-01

Page Start

1,141

Page End

1,148

Print ISSN

0070-9484

Online ISSN

2090-2360

Article File

EDJ_Volume 68_Issue 2_Pages 1141-1148.pdf

PDF . 606.9kB

Link

https://edj.journals.ekb.eg/article_227319.html

Detail API

https://edj.journals.ekb.eg/service?article_code=227319

Order

2

Type

Original Article

Type Code

254

Publication Type

Journal

Publication Title

Egyptian Dental Journal

Publication Link

https://edj.journals.ekb.eg/

MainTitle

The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study)

Details

Type

Article

Created At

22 Jan 2023