Introduction: Different surgical techniques using combinations of various materials have been utilised to gain predictable regeneration in patients suffering from periodontal disease such as Hydroxyapatite (HA) calcium phosphate (CAP) ceramics through the application of nanotechnology as well as the introduction of a modified perforated membrane (MPM)
Patients and Methods: Five patients (age 25 to 50 years old). Each patient had two contralateral intra-bony defects. Both sides were treated with open flap debridement, followed by the placement of nano hydroxyapatite graft (NanoBone, AtrossGmbH, Germany) mixed with Xenograft (Bio-Oss, Geistlich Pharma North America Inc., 202 Carnegie Center, Princeton, NJ 08540, United States). One side was covered by modified perforated membrane (PM Group), while the other side defect was covered by non-perforated occlusive membrane (OM Group). All patients were referred for immediate postoperative CBCT examination and six month follow up CBCT examination, measurements of bone level changes were performed using fusion module. Data were tabulated and statistically analysed.
Results: There was no-statistically significant difference between the two groups in mean plaque index nor in mean gingival index, PM Group showed a statistically significant higher decrease in mean probing depth compared to OM Group, There was non-statistically significant difference between the two groups in mean clinical attachment levels at baseline nor at 6 months.
Conclusion: Our study showed no statistically significant difference between the PM versus the OM regarding defect bone fill at 6 months post-operative duration showing no added benefit for the use of the modified PM regarding the maintenance of bone levels.