Aim: The present study was performed to evaluate effect of collagen cone blended with gentamicin and pure collagen cone in alveolar ridge preservation following extraction of tooth with chronic infection. Primary objective: Histological and histomorphometric evaluation of grafted bone. Secondary objective: Evaluation of changes in alveolar ridge dimensions radiographically and evaluation of primary implant stability
Subjects and Methods: Group (1): Ten extraction sockets where alveolar ridge preservation(ARP) was performed using collagen cone blended with gentamicin. Group (2): Ten extraction sockets where ARP was performed using pure collagen cone. Group (3): Ten extraction sockets where ARP was performed using xenograft and collagen membrane. Core biopsy performed during implant placement. Radiographic changes in buccolingual ridge width and alveolar crest were measured. Primary implant stability was evaluated.
Results: Significant difference in amount of new bone trabeculae between groups. Regarding radiographic buccolingual width ,significant reduction in 3 groups after 5 months. Regarding percent changes of width, collagen/gentamicin was -27,85±4,64 , collagen was -42,50±5,29 and xenograft was -15,26±4,28, the difference between groups was significant. Regarding intragroup radiographic ridge height changes significant reduction was noted in 3 groups after 5 months. Regarding percent decrease in radiographic height, collagen was (-27.38±4,92), xenograft was (-9.61±1,74) and collagen/gentamicin was (-14,66±1,71). Difference between groups was significant. Non significant difference between collagen/gentamicin and xenograft implant stability was noticed.
Conclusion: Parasorb® cone genta showed more newly formed bone. Xenograft have best results regarding volumetric changes but decreased quality of newly formed bone compared with collagen/gentamicin .