Objective: To investigate the effect of 10% and 15% Proanthocyanidin (PA) rich grape seed extract (GSE) applied for 60s and 120s and removed either by wiping or rinsing on microshear bond strength (µSBS) and color stability (ΔE).   methods: Sound bovine incisors were used in the study. The labial surfaces were ground to expose flat dentine surfaces. The specimens were divided into 9 groups; control group without any pretreatment and 8 groups pretreated with 10 % and 15% GSE, applied for 60s and 120s and then removed either by wiping with wet cotton or rinsing with water. Microshear bond strength (µSBS) was tested using a universal testing machine at a cross head speed of 0.5mm/min. A spectrophotometer was used for color measurement (ΔE) of the specimens using CIE (L*a*b*). Data were tabulated and statistically analyzed.   Results: All pretreatment groups showed significantly higher µSBS values than the control group which showed the lowest value (19.63±3.07). Group VIII showed the highest µSBS value (31.96±2.77) and the highest ΔE (3.14±0.38). All pretreatment groups showed a clinically accepted color change with a ΔE < 3.3.   Conclusion: The use of GSE in different regimens improved resin-dentin bond strength and demonstrated clinically accepted color change. The use of 15% GSE applied for 120s and wiped with wet cotton is the recommended regimen.