This project was aimed to determine the prevalence of malocclusion among school children in Cairo governorates. Materials and Methods: This study was carried out in Cairo governorate where a list of the primary schools and the number of primary school children in Cairo governorate were obtained from the database of the Ministry of Education. Cairo governorate was divided into four regions according to geographical location, two and sometimes three schools were chosen randomly from each region using SAS computer software thus, 20 schools were included in this study and a total number of 1936 schoolchildren were included in this survey. Results: Distribution of Angle classification: this study showed that 497 children (25.7%) had accepted occlusion while, 997 children had Angle Class I malocclusion representing (51.5%) of the study sample, 318 children had Angle Class II malocclusion representing (16.4%) of the study sample while 115 children had Class III malocclusion representing (5.9%) of the study sample and 9 children had Class IV representing (0.5%) of the study sample. Overjet: The most frequent category was normal overjet (>0–3.5mm) which was found to be (71.8%). Anterior open bite (<0 mm) was found in (5.9%) of the total sample. Conclusion: Compared to previous Egyptian studies, there was a tendency toward decrease in the prevalence of accepted occlusion while, there was an increase in Angle Class II and III maloc­clusion.