Objective: This study assessed the influence of titanium oxide nanofiller incorporation into
MDX4-4210 maxillofacial silicone regarding biomechanical changes.
Methods: Nano titanium oxide powder (P25, Degussa, Germany) was mixed to hightemperature-
vulcanized (HTV) silicone (MDX4-4210, Dow Corning, USA) at 0.2 wt%. For testing
the cytotoxicity, two groups of silicone specimens, ten specimens each were prepared. Group A:
Blank MDX4-4210 silicone (control group); Group B: Nano titanium oxide powder was added to
MDX4-4210 silicone; each group was assessed after 24, 48, and 72 hours. For testing mechanical
properties 60 specimens were prepared, 20 for testing tear strength, 20 for testing ultimate tensile
strength, and 20 for testing hardness. Each group was subdivided into two identical categories: (I)
10 control specimens without nano-titanium oxide, and (II) 10 experimental specimens with nanotitanium
oxide powder. The specimens were assessed and one way (ANOVA ) test was utilized to
analyze the data.
Results: After 24-hour, in the control groups, the cytotoxicity values were higher than those
of titanium oxide nanofiller group. There were marked improvements in the mean values of all the
tested mechanical properties
Conclusion: incorporating nano-titanium oxide particles improves the biocompatibility and
mechanical properties of MDX4-4210 maxillofacial silicone materials.