Aim: The aim of this study was to compare platelet rich fibrin “PRF socket plug technique"
versus the traditionally used “socket plug technique" to improve bone quality without affecting its
volumetric stability. Research question: In mandibular premolars socket preservation, will “PRF
socket plug" technique improve bone quality without affecting bone quantity, when compared to
‘socket plug" technique? Materials and Methods: This was a split-mouth randomized controlled
trial conducted on 9 patients. For each patient, bilateral socket preservation was performed. PRF
socket plug technique (intervention) was performed for one side, while the other was performed
using the traditional socket plug technique (control). After 6 months, bone and soft tissue changes
were measured. Horizontal and vertical alveolar ridge loss and loss percentage were measured
using cone-beam CT. Bone quality was measured by histomorphometric analysis of area
percentages of mineralized trabecular bone of core biopsies. Keratinized mucosa changes were
measured using Williams graduated periodontal probe. Results: Intervention group showed slightly
higher horizontal bone loss, loss percentage, vertical bone loss, loss percentage (1.36 mm, 16.98 %,
1.07mm, 7.99 %) with no statistically significant difference when compared to the control group
(1.14mm, 13.89 %, 0.97 mm, 7.21 %). Histomorphometric analysis showed higher new bone
formation (34.11 %) in intervention group compared to the control group (30.78%) with no statistically
significant difference. Both groups showed keratinized mucosa gain (1.28 mm intervention,
1 mm control) with no statistically significant difference. Conclusions: Socket plug technique
is an effective technique for alveolar ridge preservation; PRF clot represents an easy, successful,
and economical method to cover the graft in socket plug technique; PRF socket plug technique
represents a promising alternative to the routinely used socket plug technique.