Aim: To evaluate the efficiency of using platelet rich fibrin (PRF) in small chronic periapical
lesions with simultaneous immediate implant placement in maxillary anterior esthetic region.
Patients and Methods: Seven cases with small size periapical lesions in the upper anterior
aesthetic zone need immediate implantation were selected. After flapless tooth extraction and
curettage of the lesion, platelet-rich fibrin (PRF) was applied in the bony defect and TIXOS implant
was inserted simultaneously. CBCT was used immediately and 6 months post implantation to
evaluate the mean of bone density in the defect area.
Results: There was increase in the mean of bone density after six months post implantation and
it was statistical significant.
Conclusions: Platelet-rich fibrin in patients with chronic periapical lesions allow proper bone
healing with immediate implant placement in maxillary anterior aesthetic zone.