Objectives: The aim of this study was to compare the outcome of defect filling with mineralized Plasmatic matrix (MPM) versus Platelets Rich fibrin (PRF) after conservative intraosseous cystic lesions enucleation in maxillary bones.
Patients and methods: Twelve patients with large intra osseous maxillary cystic lesions were included in this study, all underwent conservative cyst enucleation. They were randomly divided into 2 groups. Group I the defect was filled with Mineralized Plasmatic Matrix (MPM), and group II the defect was filled with Platelets Rich Fibrin (PRF). Patients were evaluated clinically and radiographically at zero and 6 months postoperatively.
Results: A statistical significant decrease (p≤0.05) at cysts sizes was obvious at both groups at the follow up interval. When the groups were compared, Group I had statistically significant (p≤0.05) decrease at the cysts sizes than Group II at the follow up period.
Conclusion: MPM showed better values than PRF as a grafting material in defect filling after conservative cystic enucleation in maxillary bones.